RNase L Mediated Protection from Virus Induced Demyelination
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چکیده
منابع مشابه
RNase L Mediated Protection from Virus Induced Demyelination
IFN-alpha/beta plays a critical role in limiting viral spread, restricting viral tropism and protecting mice from neurotropic coronavirus infection. However, the IFN-alpha/beta dependent mechanisms underlying innate anti-viral functions within the CNS are poorly understood. The role of RNase L in viral encephalomyelitis was explored based on its functions in inhibiting translation, inducing apo...
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ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2009
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1000602